Efudex (Fluorouracil) Skin Cancer Treatment

The following information appears on the packaging ((Rev. August 2006) which accompanies Efudex cream, sold by Valeant Pharmaceuticals North America.

“Information for Patients: Patients should be forewarned that the reaction in the treated areas may be unsightly during therapy and, usually, for several weeks following cessation of therapy…”

“ADVERSE REACTIONS: The most frequent adverse reactions to Efudex occur locally and are often related to an extension of the pharmacological activity of the drug. These include burning, crusting, allergic contact dermatitis, erosions, erythema, hyperpigmentation, irritation, pain, photosensitivity, pruritis, scarring, rash, soreness and ulceration.”

 The following information was provided by my pharmacy, obtained by them from First DataBank, Inc.:

“SIDE EFFECTS: Skin irritation, burning, redness, dryness, pain, swelling, tenderness, or changes in skin color may occur at the site of application. Eye irritation (e.g. stinging, watering), trouble sleeping, irritability, temporary hair loss, or abnormal taste in the mouth may also occur…”